Facial infiltrating lipomatosis (FIL) is a rare congenital disorder associated with infiltration of mature lipocytes into adjacent soft tissue. Common findings include hemifacial enlargement, skeletal overgrowth, ipsilateral macroglossia, cutaneous capillary blush, mucosal neuromas, and dental changes. While benign, recurrence is common after surgical treatment. We report a case of this rare disorder and discuss the physical, radiological, and histopathological findings.
A 3½-year-old girl was found to have progressive left hemifacial enlargement since birth. Physical findings included asymmetric enlargement of the left ear, cheek, tongue, teeth, mandible, neck, and parotid and submandibular glands. In addition, hyperplastic papillae of the anterior third of tongue and premature loss of primary teeth with premature eruption of secondary teeth were noted. Otherwise, there were no neurological, audiological, or developmental abnormalities. Her prenatal course and birth were unremarkable except for polyhydramnios, and family history was negative for any known genetic disorders.
Kim J, Gottschall JA, Bachman RP, Nemzer L, Puligandla B, Schauer G. Facial Infiltrating Lipomatosis: Physical, Radiological, and Histopathological Findings. Arch Otolaryngol Head Neck Surg. 2010;136(3):301–303. doi:10.1001/archoto.2010.21
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.