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Clinical Problem Solving: Radiology
April 19, 2010

Radiology Quiz Case 1: Diagnosis

Author Affiliations


Arch Otolaryngol Head Neck Surg. 2010;136(4):413. doi:10.1001/archoto.2010.35-b

Sarcomas represent fewer than 1% of all head and neck malignant neoplasms.1,2Several features of angiosarcoma distinguish this uncommon and highly aggressive vascular sarcoma from other soft-tissue sarcomas. Although the head and neck region is the primary site for only 5% of all soft-tissue sarcomas, up to 10% of these tumors are angiosarcomas.3In contrast to most sarcomas, which tend to arise from deep tissues, 60% of angiosarcomas arise in the skin and superficial soft tissue,3,4and 50% of cutaneous angiosarcomas occur in the head and neck.4In several series, angiosarcoma was reported to be the most common sarcoma affecting the scalp.5Patients in their sixth decade of life are the most commonly affected age group.1-3The annual incidence is estimated to be 2 to 3 per million.6There is a clear white and male predilection, with a male to female ratio of 3:1.1-3

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