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Clinical Note
June 21, 2010

Lipomatous Tumors of the Parapharyngeal SpaceCase Series and Literature Review

Author Affiliations

Author Affiliations: Department of Otolaryngology, University of South Florida (Drs Rogers, Patil, and Padhya), and Department of Pathology and Cell Biology, James A. Haley Department of Veterans Affairs Hospital (Dr Strickland-Marmol), Tampa. Dr Patil is now with the Department of Otolaryngology, University of Cincinnati, Cincinnati, Ohio.

Arch Otolaryngol Head Neck Surg. 2010;136(6):621-624. doi:10.1001/archoto.2010.93

The parapharyngeal space (PPS) is a rare site for neoplasms in the head and neck, representing only 0.5% of head and neck tumors. Most commonly of parotid and neurogenic origin, tumors of the PPS are histologically diverse. Lipomas of the PPS are rare and liposarcomas rarer still. Only 5 liposarcomas of the PPS have been previously reported (Table). We describe our experience at the University of South Florida (USF), Tampa, with this unusual entity in this review of 2 lipomas, 1 pleomorphic liposarcoma, and 1 dedifferentiated liposarcoma of the PPS. To our knowledge, dedifferentiated liposarcoma has not previously been described in the PPS.

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