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Pathology Forum
December 1999

Quiz Case 1

Author Affiliations


Arch Otolaryngol Head Neck Surg. 1999;125(12):1398-1401. doi:

Congenital midline cervical cleft is a rare anomaly of the anterior aspect of the neck that may be present at any level between the mandible and manubrium. The association of a cleft with a bronchogenic cyst or respiratory epithelium is even more unusual, with fewer than 5 cases previously described in the medical literature.1-4 In 1985, Gargan et al5 reported 12 cases of congenital midline cervical cleft as part of their 30-year series of 612 thyroglossal and other branchial cleft sinuses, yielding an incidence of 1.7%. In a similar series of 198 cases by Gross and Connerly6 in 1940, only 2 midline defects were identified.

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