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May 1925


Author Affiliations

From the Department of Pathology of the Johns Hopkins University.

Arch Otolaryngol. 1925;1(5):510-520. doi:10.1001/archotol.1925.00560010534005

Clinical experience has definitely established the fact that a chronic focus of infection in the abdominal organs, the teeth, the tonsils, the nasopharynx or the accessory nasal sinuses may give rise to general systemic disorders. The local manifestations in the eye, the optic, the auditory or other nerves; the kidney, the circulatory system or the joints are often more prominent than are those of the focus from which they originate. In other words, the classical symptoms of an abscess, such as pain, redness, swelling and impairment of function, are often of little value in the localization of the primary focus of infection. It is particularly difficult, for example, to enumerate the signs and symptoms of a chronic focus of infection in the tonsil in such a way that the examining physician may decide definitely that the joint or the eye symptoms in one patient are due to the tonsil and