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PRELIMINARYREPORT ONEPHEDRINE. Presented by DR. GEORGE F. FISKE.
Most of you have seen Dr. George Fetterolf's report on ephedrine sulphate in the August number of the Archives of Otolaryngology. Dr. Fetterolf was so kind as to help me to obtain a small supply of both the chloride and the sulphate, and this is a short report of its effects on the nasal mucous membrane.
It was used on twelve persons, including myself. The solutions were 2 and 1 per cent, and 1:500. The most satisfactory and least irritating method of application seems to be a cotton pledget, rolled and saturated with the solution and then introduced into the lower meatus and left for two to three minutes in contact with the mucosa. With the 1 and 2 per cent solutions the shrinkage began immediately and was complete within two to four minutes. The contraction remained complete for from