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September 1926

EPHEDRINE IN NASAL DISTURBANCES

Author Affiliations

House Surgeon, St. Luke's Hospital NEW YORK

Arch Otolaryngol. 1926;4(3):240. doi:10.1001/archotol.1926.00590010258008
Abstract

In a recent publication by William S. Thomas,1 on a new and valuable drug in the treatment of asthma, he describes a drug, ephedrine, which is the alkaloid of the plant Ephedra vulgaris. The latter is one of the multiple drugs used for centuries by the Chinese in a tea which had a satisfactory effect in the relief of an asthmatic attack. The alkaloid ephedrine has an action similar to epinephrine, but its effect is several times as lasting. Its action in the relief of an asthmatic attack is attributed to a vasoconstriction in the bronchial mucous membrane, which diminishes the amount of secretion and the edema of the mucous membrane, thereby increasing the lumen of the air passages. The bronchoscope has proved that there is a blanching of the mucous membrane after the administration of this drug.

It was concluded that if ephedrine had such a specific

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