In a previous discussion on pemphigus of the throat by Dr. MacGruer and me,1 a case report was given which showed the perplexing symptoms and the rapid course in the acute stage of this disease. Since that time I have had a second case which closely resembles the first. As cases of acute pemphigus are still infrequent, the two cases are of enough importance to warrant a review and a comparison of their outstanding factors.
Both patients were men, one, aged 54, the other, aged 39; both were Russian Jews. The first symptoms shown by the patients were lesions in the mouth, developing shortly after the removal of a tooth; the lesions were widely distributed over the lips, gums, pharynx and larynx, although in the second patient the larynx was much more involved. The lesions were ulcerated, irregular, macerated and bleeding, the macerated mucosa giving the appearance of a