The control and safety of a general anesthetic are determined by the rapidity with which it may be introduced and withdrawn from the circulation.
For this reason, volatile anesthetic agents, such as ether, chloroform and nitrous oxide, take precedence over morphine, chloral hydrate, scopolamine, etc.
If ether is employed as a liquid temperature below 96 F., it is found that the patient's circulation may be saturated in one of severwals. Theanesthetic may be be introduced into a vein by means of Ringer's solution; it may be injected into the tissues hypodermically, or it may be mixed with oil and offered for absorption by the large bowel.
As a vapor, the anesthetic may be offered for absorption by the organs especially designed for this purpose, those in the respiratory tract. The enormous surface for absorption offered by the respiratory tract (a surface equivalent to the outside surface of a balloon
FLAG PJ. INTRATRACHEAL INHALATIO ANESTHESIA: THE METHOD OF ELECTION FOR OPERTIONS ON THE HEAD AND NECK. Arch Otolaryngol. 1928;7(2):156–164. doi:10.1001/archotol.1928.00620010168009
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