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Article
August 1928

Progress in OtolaryngologyA Summary of the Bibliographic Material Available in the Field of OtolaryngologyINTRADURAL DISEASES IN RELATION TO RHINOLOGY AND OTOLOGYA CRITICAL SURVEY OF THE RECENT LITERATURE

Arch Otolaryngol. 1928;8(2):193-235. doi:10.1001/archotol.1928.00620020209012
Abstract

I. ADVANCES IN THE KNOWLEDGE OF THE PHYSIOLOGY OF THE CEREBROSPINAL FLUID TENSION

Future advances in the surgical treatment of suppurative diseases of the brain will depend largely on the utilization of the physiologic factors influencing the central nervous system.

A. NORMAL VARIATIONS IN THE FORMATION OF CEREBROSPINAL FLUID AT DIFFERENT HOURS OF THE DAY

Hart1 has demonstrated clinically that there is a marked variation in the formation of cerebrospinal fluid for the different periods of the day and night, there being a decrease in the early morning and afternoon, an increase in the forenoon and evening, with cessation in the formation of the fluid for the first few hours after midnight. He thinks that the variations in the amount of fluid formed is probably related to general vital activity, and possibly parallels the blood pressure curve. Air, blood, etc., should be classed as irritants which upset

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