Migraine has been known as such almost since the beginning of the knowledge of medicine. Liveling,1 in his classic book, described migraine as a unilateral or bilateral headache, beginning usually at the age of puberty, seldom after the age of 30, and continuing until middle life. It is characterized by periodic attacks and is usually accompanied by prodromal symptoms. Exciting causes may be gastro-intestinal disorders, menstrual periods, emotional disturbances or physical or mental strain. It varies from a mild headache to severe prostration with nausea and vomiting. Visual symptoms consisting of distortions of the visual field and psychic disorders may precede the pain. The case given below seems to fall under this classification. The severe attacks began with the first menstruation; they were periodic, and gradually increased in severity, and the patient was able to determine each impending attack. Visual symptoms, however, did not occur. Several members of the