The complication of the gravest importance which concerns the otologist is probably the invasion of the subarachnoid spaces by infecting organisms and the subsequent progressive suppurative meningitis. It is a disease of such serious consequences that any light, no matter how small, which might be shed on it may be welcomed, with the hope of a clearer illumination in the future. At best, the mortality in all varieties of septic meningitis is excessively high. It will run well over 90 per cent, and in many forms will probably be more than 95 per cent. In 1921, Eagleton1 was able to collect reports of cure in only thirty cases of purulent meningitis following operation. It is true acute suppurative meningitis with the infecting organisms proliferating and elaborating their toxins in the subarachnoid space that demands one's attention.
The lethal effects of this invasion are due to three distinct and yet
WOOD EL. THE SUBARACHNOID SPACES IN RELATION TO OTITIC MENINGITIS. Arch Otolaryngol. 1929;9(1):40–56. doi:10.1001/archotol.1929.00620030048004
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