The symptom of intermittent nasal obstruction is particularly annoying at night and is usually associated with a slight nasal discharge and occasional attacks of sneezing. These patients are sensitive to the slightest atmospheric changes and at times are quite free from symptoms. The intranasal examination reveals turgescence of the nasal mucosa, especially over the inferior turbinals, and there is also thickening of the mucous membrane over the septum. The membranes shrink readily under the administration of epinephrine, and there are no actual hypertrophies. Subacute sinusitis is responsible for some of these conditions, and this is benefited by measures leading to improvement in aeration. However, poor hygienic conditions are almost always a factor and probably the most important cause of this obstruction.
The situation is a difficult one to handle and calls for general treatment as much as local therapy. Hygienic surroundings must be improved; the patients must have fresh air,
HARRIS ML. ZINC IONIZATION AS A TREATMENT FOR INTERMITTENT NASAL OBSTRUCTION. Arch Otolaryngol. 1929;10(1):75–76. doi:10.1001/archotol.1929.00620040085011
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