Of the various conditions of the eye due to disease of the sinuses none are so well recognized or established as the diseases of the optic nerve. It has been several years since Onodi (1904) and others demonstrated the close relationship of the optic nerve to the sphenoid and posterior ethmoid cells. Since then, a large accumulation of clinical cases has shown that the causal relationship exists beyond question. There are today few ophthalmologists of experience who on seeing an inflammation of the optic nerve do not send the patient to a rhinologist for a report as to the presence of ethmoiditis or sphenoiditis. Many times a positive report is returned, but on other occasions nothing suggestive of disease is found in the nose. This happens so frequently that evidently there is a large class of cases in which no intranasal symptoms occur, or else they are peculiarly difficult
THOMSON ES. CONDITIONS OF THE OPTIC NERVE CAUSED BY DISEASE OF THE SINUSES. Arch Otolaryngol. 1929;10(3):248–261. doi:10.1001/archotol.1929.00620060044004
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