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OTOLOGY ANDNEUROLOGY. Dr. J. GORDONWILSON, Chicago.
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EARLYSTAGES IN THEDEVELOPMENT OF THEACOUSTICAPPARATUS IN THEHUMANEMBRYO. DR. GEORGE L. STREETER, Carnegie Laboratory of Embryology.
Of the various sense organs the ear is the first to make its appearance in the human embryo. As the first somites begin to show, and before the closure of the neural tube, that part of the neural wall that is to furnish the acousticofacial ganglion exhibits an active proliferation of its cells, producing a lateral bulging. From the lateral surface of this fold the ganglion mass becomes detached by delamination. Coincident with this, an area of thickened skin ectoderm becomes demarcated as the otic plate. The progressive differentiation of this otic plate and its invagination and detachment from the surface ectoderm have been photographed and demonstrated in a series of twenty-four embryos, ranging from the stage of 7 somites to embryos 4 mm. long, at which time the otic vesicle
SONNENSCHEIN R, WILSON JG. AMERICAN OTOLOGICAL SOCIETY. Arch Otolaryngol. 1929;10(6):693–710. doi:10.1001/archotol.1929.00620090135009
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