The subject of agranulocytic angina was carefully presented before the Section on Otolaryngology by Hunter1 in 1925 and by Houser and Rose2 in 1928. The propriety of considering agranulocytic angina as a separate syndrome distinct from other types of agranulocytosis (or sepsis with granulocytopenia) is admittedly open to question, as pointed out by Krumbhaar in a discussion of Hunter's paper. We believe, however, that the condition first clearly recognized by Schultz,3 of Berlin, in 1922 is sufficiently distinct to warrant, at least for the present, a specific designation. Our remarks, therefore, will be concerned chiefly with this symptom-complex known as agranulocytic angina and not with the more variegated pictures of agranulocytosis in general.
The literature of the past few years presents a rapidly increasing number of case reports, now more than a hundred. Some of these were instances of agranulocytosis without angina, some were cases of