The so-called mixed tumors are characterized by epithelial cells of various types arranged in masses, strands and alveoli and a dense hyaline or myxomatous stroma which often includes cartilage or even bone. These are generally regarded as typical neoplasms of the salivary glands, particularly of the parotid; but they are also encountered in other parts of the body, especially in the kidneys and genital tract.
Mixed tumors occurring about the face and buccal cavity not associated with the large salivary glands have been described in the soft palate by Coenen,1 D'Aunoy2 and others; in the tongue by Brunschwig;3 in the orbit and lacrimal glands by von Graefe,4 Barbezat,5 and Verhoeff.6 Subcutaneous mixed tumors also occur about the face, but are not commonly recognized and hence are not usually considered in the differential diagnosis of small superficial nodules. A review of the literature would indicate
BRUNSCHWIG A. SUBCUTANEOUS MIXED TUMOR OF THE FACE NOT ASSOCIATED WITH SALIVARY GLANDS. Arch Otolaryngol. 1931;13(1):52–58. doi:10.1001/archotol.1931.03660010062005
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