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Article
March 1931

GRADENIGO'S SYNDROME: WITH A CONSIDERATION OF "PETROSITIS"

Author Affiliations

SANTA BARBARA, CALIF.

Arch Otolaryngol. 1931;13(3):347-378. doi:10.1001/archotol.1931.04230020033003
Abstract

In 1904 Gradenigo called attention to a definite clinical entity, namely, a suppurative otitis media complicated by involvement of the abducens and trigeminus nerves on the corresponding side. In the February, 1924, issue of the Laryngoscope, I reported a case with this triad; the patient recovered after a simple mastoidectomy. The incentive to the writing of this paper was an analysis of a second case with this syndrome, in which meningitis developed and the patient died; an autopsy was performed, and the temporal bone was removed with the corresponding side of the sella and cavernous sinus. This and two other cases stimulated anatomic studies of the petrous cells and adjacent structures at the apex. I made dissections, therefore, of the temporal bones of 5, 6 and 7 month fetuses, two full term infants and fifty adults.

One must consider the anatomy of the petrous bone and the structures at its

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