The normal secretions of the sinuses is a grayish, viscous fluid that bathes the entire lining membrane, protecting it and assisting the ciliated epithelium in the removal of foreign substances. The physical properties of this fluid and its rôle in the protection of the sinuses have been studied by Yates,1 Walthard2 and Stark.3
Bacteriologic observations by Törne,4 Frankel,5 Calamida and Bartarelli,6 and Linton7 indicate that the normal nasal sinus is usually sterile. The important rôle played by the ciliated epithelium in producing this result is recognized; however, it has long been suspected that some antibacterial substance in the secretions is a contributing factor. It was the object of this study to determine whether such a substance exists, and, if it does, to find out something of its nature.
According to Hilding,8 the normal histology of the sinus in man
LINTON CS. BACTERIOSTATIC PROPERTIES OF THE SECRETIONS OF THE SINUSES. Arch Otolaryngol. 1932;15(2):190–201. doi:10.1001/archotol.1932.03570030207002
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