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Article
October 1932

EFFECTS OF RADIATION ON ALLERGIC NASAL MUCOSA

Author Affiliations

Director of the Tumor Clinic, Michael Reese Hospital CHICAGO

Arch Otolaryngol. 1932;16(4):561-565. doi:10.1001/archotol.1932.00630040573011
Abstract

The treatment of vasomotor rhinitis by medical, surgical and allergic methods has been uniformly disappointing. The pathologic changes underlying this syndrome are well known; they consist of epithelial hyperplasia of the nasal mucosa, edema of the subepithelial tissue and dilatation of the intercellular spaces, mucous glands and capillaries. A consideration of the known effects of radiation on normal and pathologic nasal mucous membrane suggested the use of radium in an attempt to correct the local pathologic conditions encountered in allergic nasal disease. The purpose of this communication is to describe the gross and microscopic effects of radiation on the allergic nasal mucosa, and to report the clinical results obtained by irradiation in forty cases of vasomotor rhinitis.

The morphologic appearance of the nasal and sinus mucosa in vasomotor or hyperesthetic rhinitis is similar to that encountered in the bronchial mucosa in bronchial asthma. Among others, Hansel1

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