The several histologic features which conjointly characterize otitic sclerosis, or "otosclerosis," are now well recognized, and their occurrence has been described in a recent and detailed résumé of the pertinent otologic literature.1 The association of the following features, which individually are not limited to bone called sclerotic, constitutes a disease which is seemingly peculiar to the osseous labyrinth: The diseased bone stains intensely; it is richly vascularized by relatively large thin-walled vessels lodged in wide and freely communicating spaces; the spaces are enclosed by definite lamellar systems; the diseased area is quite sharply delimited (by the features just mentioned) from the normal bone in which it is embedded; although bearing some resemblance to a neoplastic formation, the mass is but mildly invasive, not necessarily deforming and usually restricted to certain portions of the capsule; it is not accompanied by an inflammatory reaction.
These, as well as other familiar, but
WILSON JG, ANSON BJ. FORM AND STRUCTURE OF AN AREA OF OTITIC SCLEROSIS IN THE TEMPORAL BONE OF AN ADULT. Arch Otolaryngol. 1933;18(3):291–297. doi:10.1001/archotol.1933.03580060313003
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