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September 1933


Arch Otolaryngol. 1933;18(3):381-408. doi:10.1001/archotol.1933.03580060403014

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Pathologic Anatomy and Pathogenesis of Otosclerosis. Dr. Otto Mayer, Vienna, Austria.  The osseous neoplasm in otosclerosis is resorptive, consists primarily of endochondral bone and develops in the cavities and arches of the otic capsule in the form of foci or cords which surround this area in ringlike formation. It is classified under tumorous hyperplasia because of the construction and inclination to hyperplasia. A small accumulation of endochondral tissue at the point of origin of the neoplasm presents as a type of tissue malformation, from which the neoplasm develops, the hamartoma of E. Albrecht and the hamartoplasia of M. Weber. The neoplasm originates in the margins of the fenestra and the arches of the osseous capsule of the labyrinth. From the standpoint of structure this development is strongly mechanical. Fissures are found in the same places as a result of mechanical taxation of the bone. Thus the osseous neoplasm in otosclerosis

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