Acute inflammation of the paranasal sinuses is probably as common as the common cold. In most instances it is probably as transient. Chronic sinusitis is, however, also an extremely common disease. While at times a purely local condition, it is often associated with other diseases of the respiratory tract, diseases to which the sinus condition may be secondary, or in the causation of which the sinus disease may play a part.
A prime and obvious factor in the production of chronic sinus disease is bacterial invasion. A second well recognized factor is the presence of an intranasal anatomic abnormality, such as marked septal deflection, which interferes with the free drainage of the sinuses. Repeated infection associated with the anatomic defect serves in time to destroy the ciliated epithelium of the sinuses, putting out of action an important mechanism in normal drainage of the sinuses, and thereby tending to make the
KERN RA, SCHENCK HP. CHRONIC PARANASAL SINUS INFECTION: RELATION TO DISEASES OF THE LOWER RESPIRATORY TRACT. Arch Otolaryngol. 1933;18(4):425–429. doi:10.1001/archotol.1933.03580060457002
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