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Article
October 1933

PRINCIPLES UNDERLYING CILIARY ACTIVITY IN THE RESPIRATORY TRACT: I. A METHOD FOR DIRECT OBSERVATION OF CILIA IN SITU AND ITS APPLICATION

Author Affiliations

ST. LOUIS
From the Department of Anatomy, Washington University School of Medicine.

Arch Otolaryngol. 1933;18(4):516-524. doi:10.1001/archotol.1933.03580060548008
Abstract

It is in keeping with the generally increasing conservatism in the treatment of sinusitis and other nasal disorders that investigations of the fundamental principles applicable to the ciliated and secretory elements of the mucous membrane lining the respiratory tract should be made available. It is important to know what the primary effect of many reagents on the cellular elements of the membrane is, the rôle played by the nervous system in regulating ciliary activity, the adaptability of injured and regenerated tissue to changes in the environment and many other equally significant cytophysiologic relationships of this tissue. This series of publications, based on investigations of the past several years and the new problems resulting from earlier studies dealing with the phases of the subject already mentioned, is presented primarily to meet the needs of the rhinologist.

Numerous methods have been employed in the last hundred years to evaluate ciliary activity. A

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