This paper deals with the diagnosis, treatment and end-results in 21 cases of primary malignant tumor of the maxillary sinus. The patients were treated by the department of roentgenology of the Hospital of the University of Pennsylvania. Surgical procedures, when indicated, were performed by the department of otolaryngology of the same hospital. Tumors having their origin outside the antrum were excluded from this series. In a few advanced cases, especially when both the maxillary and the ethmoid sinuses were involved, it was impossible to determine with certainty that the antrum was affected first.
Although it had long been known that tumors of the antrum of Highmore occurred, it was not until 1898, when Phillips1 presented his paper on this subject, that any comprehensive consideration of this particular lesion was attempted. At this time 16 cases found in the literature and a case observed by the author were reported.
HOUSER KM. DIAGNOSIS AND TREATMENT OF PRIMARY MALIGNANT NEOPLASMS OF THE MAXILLARY SINUS. Arch Otolaryngol. 1933;18(5):643–650. doi:10.1001/archotol.1933.03580060685006
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