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Article
February 1934

HISTOPATHOLOGY AND CLINICAL INTERPRETATION OF EXPERIMENTAL SINUS DISEASE

Arch Otolaryngol. 1934;19(2):183-194. doi:10.1001/archotol.1934.03790020029003
Abstract

This research has during the past year been directed along several lines:

  1. Acute frontal sinusitis was produced in well nourished cats maintained for two months on the following diets: a diet rich in vitamin A, an excess acid diet, an excess base diet, a high sodium diet and a high potassium diet. These diets were accurately planned, measured and administered under controlled conditions in accordance with lists made up by Dr. Ira Manville of the department of physiology. Little change in the physical condition of the animals was caused by the diverse diets, and no diet seemed to arrest or otherwise influence the development and continuance of chronic changes in the membranes of the sinuses. In the animals fed a basic diet, however, the more severe cases of snuffles and lacrimation were noted. Somewhat less gross disturbance was noted in the animals fed the acid diet, the sodium diet

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