[Skip to Navigation]
February 1934


Author Affiliations


Arch Otolaryngol. 1934;19(2):195-200. doi:10.1001/archotol.1934.03790020041004

Tuberculosis is almost unique among infections, in that it has, properly speaking, no period of incubation. Infection of the body is accomplished, and the anatomic marks of infection come into being, and may remain indefinitely long (for months, years or a natural life-time), and the body meanwhile never exhibit symptoms of the disease. On the other hand it is certain that, when active tuberculosis does make its appearance, in the vast majority of cases it is the expression of an infection that originated a comparatively long time previously (weeks, months, or even years before), and during all this time has resided in the body in a state of clinical quiescence, that is, without noticeable effect on the body economy.1

The foregoing fact really owes its recognition less to clinical observation than to a laboratory method, the "tuberculin reaction." A definite reaction to tuberculin is generally accepted as a proof

Add or change institution