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September 1935

Chronic Nasal Sinusitis and Its Relation to Mental Disorder.

Arch Otolaryngol. 1935;22(3):400. doi:10.1001/archotol.1935.00640030414017

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The material forming the basis of this monograph consists of the observations at autopsy on 471 patients dying in institutions for mental disease. Of these, according to Pickworth, 314, or 66 per cent, presented evidence of some inflammatory disease, active, healed or latent, of one or more of the nasal sinuses. It is his contention that this association is more than fortuitous, and the inference is made that in each of these cases the sinus involvement stands in direct causal relationship to the mental disorder. A great deal of heterogeneous data, some factual but much pure assumption, are brought together to support this thesis. On the whole, the work is uncritical to the point of being naïve.

In the first place, the incidence of sinus disease in insanity as found by this author is much higher than that generally quoted elsewhere. It is the sphenoid sinus which is most

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