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Article
October 1935

LATE CHANGES IN THE MUCOSA OF THE FRONTAL SINUSES AND NOSE OF DOGS FOLLOWING IONIZATION

Arch Otolaryngol. 1935;22(4):454-465. doi:10.1001/archotol.1935.00640030470008
Abstract

The value of ionization as a sound method of treatment of allergic conditions of the nose should be judged not only by the amount of relief from local symptoms which follows but by the derogatory effects which it may bring about in the tissues. Too often an unsound empirical method has been adopted solely because of enthusiasm for something new or sensational, and one has eagerly rushed to apply the method of cure while it was still in vogue.

There are certain fundamental laws governing tissue reactions which may not be ignored, and those concerned with the reaction of repair in connective tissue are the most inflexible. The ever-present anxiety to prevent the formation of adhesions and synechiae following an operative procedure is evidence of a tacit respect for these laws. While it is readily acknowledged that interference with function is caused by fibrosis within the parenchymatous visceral organs, the

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