The practical importance of the regeneration of the mucous membrane of the paranasal sinuses, aside from its interest from an academic point of view, is real and readily apparent. The local results of an operation which removes the mucous membrane of the paranasal sinuses should be of great interest to the otolaryngologist. If investigation shows that following radical surgical intervention on a sinus the mucous membrane regenerates in a more or less normal form, there is further justification for adequate surgical intervention.
What apparently has been until recently the prevailing opinion concerning postoperative regeneration of the mucous membrane of the paranasal sinuses was expressed by Carter1 in 1930, when he wrote : "Bare bone does not procure for itself another periosteum, nor does it remain alive. Ciliated epithelium once destroyed is never regenerated. Normal mucous glands do not reappear in the scar tissue which follows the
BROWNELL DH. POSTOPERATIVE REGENERATION OF THE MUCOUS MEMBRANE OF THE PARANASAL SINUSES: A SUMMARY OF THE PUBLISHED INVESTIGATIONS. Arch Otolaryngol. 1936;24(5):582–588. doi:10.1001/archotol.1936.00640050595003
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