The ability of the membrana tympani to reconstruct itself is exceeded only by its failure to do so in some instances. In the same hour I have observed a minute perforation of several years' duration, and a "new growth" membrane which had formed after a radical operation on the mastoid, the membrane extending from the anterior wall of the canal to the posterior wall of the mastoid cavity, completely partitioning the tympanum, with a surface area about equal to that of a 5 cent piece. This membrane was perfectly transparent, apparently consisting only of the epidermal layer, growing posteriorly from a vestige of the anterior border, as proliferation proceeds only in this direction. How so frail and poorly nourished a reconstruction was possible when the minute perforation consisting of all the layers with an abundant blood supply failed to close can be explained on the basis of
STINSON WD. REPARATIVE PROCESSES IN THE MEMBRANA TYMPANI: SOME INTERESTING MANIFESTATIONS. Arch Otolaryngol. 1936;24(5):600–605. doi:10.1001/archotol.1936.00640050613006
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