In 1931 the results of acute experimental fixation of the membrane of the round window in animals were reported,1 and the following year a further report was made of the effect of placing tissue grafts in the niche of the round window.2 In the later experiments the animals were kept alive until the grafts had been in place sufficiently long to take, and the hearing was then tested. In many instances, in which the graft was proved microscopically to have actually grown in its new position, there was a striking increase in the functional ability of the treated ear over that of the normal ear. Such measurements were made by estimation of changes in electrical potential in the auditory nerve after acoustic stimulation of the animal's ear. The technical details of the method will be found in the articles mentioned.
These observations have been confirmed repeatedly, and the phenomenon, whatever
HUGHSON W. GRAFTS IN THE ROUND WINDOW IN THE TREATMENT OF CERTAIN TYPES OF DEAFNESS. Arch Otolaryngol. 1937;25(6):623–631. doi:10.1001/archotol.1937.00650010717003
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