This experimental work was performed to determine the fate of human costal and septal cartilage preserved in alcohol and transplanted beneath the skin of other human beings.
The use of cartilage preserved in alcohol to fill depressions of the nose, face and skull, like most surgical procedures, is not new. It was utilized rather extensively a generation ago and was discarded because of the belief that the grafts either suppurated or were absorbed and replaced by fibrous tissue. Recently there has been a revival of the method. J. B. Brown,1 Clair Straith, C. R. Straatsma and I have used cartilage preserved in alcohol to repair saddle nose and defects of the skull.
Successful grafts examined by external palpation appear to retain their size and consistency up to periods of over a year. The advantage of this procedure is obvious, as fresh cartilage from cadavers is easily obtainable in almost any
PEER LA. CARTILAGE TRANSPLANTED BENEATH THE SKIN OF THE CHEST IN MAN: EXPERIMENTAL STUDIES WITH SECTIONS OF CARTILAGE PRESERVED IN ALCOHOL AND BURIED FROM SEVEN DAYS TO FOURTEEN MONTHS. Arch Otolaryngol. 1938;27(1):42–58. doi:10.1001/archotol.1938.00650030049003
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