During the period immediately prior to and following the World War, considerable emphasis was given to the surgical treatment of infection of the blood stream complicating acute and chronic mastoiditis. Little attention was given to the medical therapy. The modern trend, however, is in the direction of a more efficient application of various medical procedures.
The nearest approach to the ideal medical treatment at this time is the transfusion of whole immunized blood from compatible convalescent donors. A careful study of the blood is essential to the successful management of this condition. The knowledge of the nature of the initial infection determines to some degree the possibility of septicemia's developing and to some extent the type of treatment necessary. Cultures of the blood, when properly made, constitute one of the most valuable laboratory aids, but a positive or negative culture should not be the deciding factor in the management of
GILL EG. INFECTION OF THE BLOOD STREAM: MEDICAL TREATMENT, WITH SPECIAL REFERENCE TO TRANSFUSIONS OF IMMUNIZED BLOOD; REPORT OF CASES. Arch Otolaryngol. 1938;27(1):67–82. doi:10.1001/archotol.1938.00650030074005
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