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April 1938


Arch Otolaryngol. 1938;27(4):504-515. doi:10.1001/archotol.1938.00650030515015

Otolaryngologic Manifestations of Hemophilia. Dr. Carroll L. Birch (by invitation).  Hemophilia is usually classified under the hemorrhagic diatheses. It is characterized by habitual hemorrhage from various parts of the body, which may be spontaneous or may follow injury. The hemorrhage is excessive and out of all proportion to the extent of the injury. The hemorrhagic manifestations usually begin early in life. In my experience with 107 patients with hemophilia, 30 per cent had hemorrhages within the first three weeks of life, while 85 per cent had hemorrhages within the first three years.This disease is hereditary and is linked with sex in its transmission. Only males have the disease, but it is transmitted by the unaffected female. All the daughters of a hemophiliac become transmitters of the defect. Theoretically, 50 per cent of their daughters become transmitters like themselves. Hemophilia is never transmitted through the normal male and is never

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