Bilateral acoustic neurofibromas, although not rare, are uncommon as compared with the unilateral lesions of this type and respond more satisfactorily to palliative surgical procedures. Since 1910, 152 proved cases of tumor of the eighth cranial nerve have been observed at the Mayo Clinic. The tumor was bilateral in only 2 of these cases; in both it was associated with generalized neurofibromatosis without a hereditary background.
Bilateral tumor of the cerebellopontile angle was recorded first by Wishart1 in 1822 and by Knoblauch2 in 1843. Later it was described in more detail by Henneberg and Koch,3 in 1902. In 1912 Henschen4 described 136 cases of unilateral and 19 cases of bilateral tumor of the cerebellopontile angle. In 1915 he was able to add 109 additional cases of unilateral tumor and 5 cases of bilateral tumor which made a total of 245 cases of unilateral acoustic tumor and 24 cases of bilateral
CRAIG WM, STEENROD EJ. BILATERAL ACOUSTIC NEUROFIBROMAS. Arch Otolaryngol. 1938;28(3):404–411. doi:10.1001/archotol.1938.00650040413010
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: