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Article
October 1939

FURTHER EXPERIMENTS IN THE ACTION OF DRUGS ON THE NASAL MUCOSA

Arch Otolaryngol. 1939;30(4):509-515. doi:10.1001/archotol.1939.00650060555002
Abstract

The following report is supplementary to one of a similar nature made a few years ago.1 The original communication dealt with the effects of several of the more commonly used drugs on the ciliary activity of the nasal epithelium. Four of the drugs the effects of which are described at this time are in general use; four others are not now part of the rhinologist's pharmacopeia but are included here for other reasons, which will be explained.

The methods employed in these investigations are practically identical with those which are described in detail in the first paper. As in the first instance, three parallel series of experiments were done, the first on the living animal membrane undisturbed in the sinus, the second on material extirpated from animals and the third on material extirpated from the human nose. When the results of these three are identical, it is felt that they

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