Paget's disease, or osteitis deformans, first described in 1877, is a disease of unknown cause, usually affecting a number of bones and occurring in patients over 40 years of age. It may be1 a general disorder in which at present only the osseous changes are known. Formerly considered rare, it is known to be merely unusual, and with more roentgenograms the disease, no doubt, will be recognized oftener, particularly in its earlier stages. Osteitis deformans affects especially the skull, vertebrae and bones of the leg although it may be confined to one bone. The sacrum, spinal column, femur and cranium are oftenest affected,2 but the disease may commence in the skull or maxilla.
Although the cause is unknown, it is thought by some that the disease has a vascular origin (endarteritis), possibly embolic, so closely do the lesions resemble the distribution of carcinomatous metastases in bone. Others, because of the
CHILDREY JH. PAGET'S DISEASE OF THE BONES OF THE SKULL WITH OBLITERATION OF THE SINUSES. Arch Otolaryngol. 1940;31(2):333–338. doi:10.1001/archotol.1940.00660010335009
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