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March 1940

NASOPHARYNGEAL CARCINOMA: Extension Intracranially and Metastasis by Implantation into the Soft Palate; a Clinical and Pathologic Study

Author Affiliations

From the Department of Pathology, Cook County Hospital, and the Department of Laryngology, Rhinology and Otology, Research and Educational Hospitals, University of Illinois College of Medicine.

Arch Otolaryngol. 1940;31(3):529-539. doi:10.1001/archotol.1940.00660010533014

The following case of carcinoma of the nasopharynx presents several features interesting not only to the otolaryngologist but also to the neurologist, the ophthalmologist, the roentgenologist and the pathologist. It is presented because of its value to both the clinician and the pathologist in that an attempt has been made to explain clinical symptoms from a complete study at autopsy.

Of further interest was the intracranial extension of the tumor with marked destruction of bone, metastasis to the liver and an apparent implantation of tumor cells by contact from the growth in the nasopharynx to an ulcer on the nasal surface of the soft palate. This ulcer approximated and was irritated by the tumor in the nasopharynx on phonation and swallowing.

That malignant tumors of the nasopharynx are not uncommon is evidenced by the abundance of literature on the subject, many authors reporting fairly large series of cases. It was

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