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May 1940


Author Affiliations

From the departments of otolaryngology and medicine, Hospital of the University of Pennsylvania.

Arch Otolaryngol. 1940;31(5):855-857. doi:10.1001/archotol.1940.00660010869007

Pulmonary suppuration following tonsillectomy may result from embolism or from inhalation of septic material. In either event the development of pulmonary abscess is most serious. The following case, we believe, represents the successful termination, by treatment with sulfapyridine (2-[para-aminobenzenesulfonamido]-pyridine), of ominous pulmonary suppuration resulting apparently from post-tonsillectomy embolism.

REPORT OF A CASE  Miss G., 42 years of age, was operated on by one of us (K. M. H.) on June 27, 1939. The operation was an uncomplicated tonsillectomy with local anesthesia (injection of nupercaine in oil around the tonsillar capsules). The patient's preoperative status was "normal" (routine physical examination, blood count, urinalysis and temperature record). For twenty-four hours after operation she was afebrile and in apparently satisfactory condition. At midnight the second night after operation she had a severe chill, and her temperature rose to 104 F. (axillary). From this time (June 29) septic fever, chills, sweats and prostration