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September 1940


Arch Otolaryngol. 1940;32(3):472-483. doi:10.1001/archotol.1940.00660020476005

Infectious mononucleosis is an acute self-limited disease which is so frequently associated with symptoms and signs involving the upper part of the respiratory system that it should be constantly kept in mind by the laryngologist. It is in the hope of promoting closer cooperation between the laryngologist, the hematologist and the serologist that this study of 9 cases is presented.

HISTORICAL DATA  In 1889 Pfeiffer1 described a condition, characterized by a short febrile course and enlarged tender cervical lymph nodes and occurring in house epidemics, which he called "Drüsenfieber." During the following twenty years there were numerous references in the literature to the condition called glandular fever.2In 1896, West3 reported an epidemic of 96 cases of a febrile disease lasting nine to twenty-seven days and accompanied by enlargement of the cervical lymph nodes. In some instances abdominal tenderness and frequently enlargement of the spleen and liver were noted. Recovery

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