Every practitioner of otorhinolaryngology is from time to time confronted by cases in which the causation is so obscure that diagnosis presents seemingly insurmountable difficulty. When all organic causes have been eliminated and treatment of the organs involved has not given satisfactory results, the possibility of allergic complications should always be considered. Particularly should the clinician confronted with irritability or actual disturbance of function in the ear, nose or throat consider the possibility of gastrointestinal disturbance as the chief etiologic factor. Interference with the physiologic function of the gastrointestinal tract frequently sets up a toxic condition in the lower part of the bowel which causes it to become a reservoir for infection, later to be conveyed by the lymphatic and vascular systems to distant parts of the body. An intimate relation exists between the gastrointestinal tract and the ear, nose and throat, which makes such infection peculiarly apt to find
GATEWOOD WL. SYMPTOMS OF GASTROINTESTINAL ORIGIN IN THE EAR, NOSE AND THROAT. Arch Otolaryngol. 1941;33(4):592–599. doi:10.1001/archotol.1941.00660030600008
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