Since surgical procedures offer the best results in the treatment of malignant growths of the larynx, particularly those of the intrinsic type, some anesthetic must be employed. Of course when irradiation, the only other method for treatment for malignant diseases of the larynx, is employed, the use of an anesthetic is unnecessary. But irradiation, in spite of the recent advances in its use and the claims of cure which are made for it, should be used only when surgical intervention is inadvisable because the patient is a poor surgical or anesthetic risk or because the malignant condition is hopelessly advanced. No one denies that surgical intervention is the method of choice if the patient can be reasonably assured of a cure.
The operation for cancer of the larynx is necessarily a major opertion and is attended by some dangers. Besides the complications incident to the operation itself, such as bleeding
KEMLER JI. NITROGEN MONOXIDE AND OXYGEN FOR ANESTHETIZATION IN OPERATIONS FOR MALIGNANT GROWTHS OF THE LARYNX. Arch Otolaryngol. 1941;33(5):707–710. doi:10.1001/archotol.1941.00660030717003
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