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May 1941


Arch Otolaryngol. 1941;33(5):892-904. doi:10.1001/archotol.1941.00660030902020

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Otosclerosis in Identical Twins. Dr. Elmer W. Hagens.  This article will appear in full in a later issue of the Archives.

DISCUSSION  Dr. George E. Shambaugh Jr.: Identical twins develop from a single ovum, so that presumably all inherited factors are shared equally. It would seem that otosclerosis in identical twins offers the ideal opportunity for determining the importance of heredity in comparison with external factors in this mysterious disease. However, there may be one complicating factor in the situation. It is said that identical twins are no more alike than are the left and the right side of a person, since one twin develops from the right half of the ovum at its first division and represents the right half of the person originally intended, while the other twin represents the left half. Deafness in otosclerosis is not always symmetric but frequently develops earlier or more rapidly in one

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