Acute laryngotracheobronchitis is an infection of the respiratory tract, occurring most frequently in children under 2 years of age and characterized usually by primary inflammation of the pharynx, with later involvement of the larynx and trachea and extension to the bronchi. A sticky, gummy exudate produces variable respiratory obstruction, with severe symptoms of toxicity. The cause has not been determined definitely, but many organisms obtained from the laryngeal and tracheal cultures have been considered as causative factors. Recently, it has been suggested that a virus is the primary invader, preparing the way for secondary bacterial invasion, especially by the hemolytic streptococcus.Greenwood1 stated: "Acute laryngitis in infants is an inflammatory disease of the laryngeal intima, usually secondary to an acute upper respiratory infection, and generally associated with pathological changes in the lower respiratory tract." Jackson has divided acute inflammations of the larynx, per se, into (a) specific acute laryngitis
ORTON HB, SMITH EL, BELL HO, FORD RA. ACUTE LARYNGOTRACHEOBRONCHITIS: ANALYSIS OF SIXTY-TWO CASES WITH REPORT OF AUTOPSIES IN EIGHT CASES. Arch Otolaryngol. 1941;33(6):926–960. doi:10.1001/archotol.1941.00660030937003
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