Isolated amyloid tumor of the larynx is not common. According to Ewing, "extensive amyloid degeneration appears to overtake fibromas, chondromas, occasionally sarcomas, and some chronic productive inflammatory processes, so that the cellular structure is almost completely replaced by bulky masses of amyloid." Involvement of the air passages is not uncommon. Cases have been reported of the occurrence of such a tumor in the larynx, the trachea, the base of the tongue and the nares. The most common sites are the larynx and nares. In amyloidosis, commonly associated with prolonged suppuration, the distribution often is widespread.
The following case is of interest since it represents an isolated amyloid tumor unassociated with demonstrable local disease or generalized amyloidosis and suggests the idiopathic form.
REPORT OF A CASE
History.—A man aged 48, a locomotive inspector, had had a husky voice for many years. After a cold, three years before admission to the
CLERF LH. AMYLOID TUMOR OF THE LARYNX. Arch Otolaryngol. 1942;36(3):377–380. doi:10.1001/archotol.1942.03760030073006
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