This paper is presented in the belief that infections about the head by anaerobic and microaerophilic streptococci are more important than is generally appreciated. Also, the behavior of these organisms may explain some of the doubtful factors in the pathogenesis of infection of cranial bones. If these anaerobes are responsible for such infections, it is likely that their control will be considerably helped by measures shown effective against such anaerobes elsewhere, particularly by the use of zinc peroxide. Conversely, the observation that zinc peroxide seems to be effective in the control of infection of the cranial bones in at least some cases should help strengthen the case against anaerobes.
My earlier experience with frontal osteomyelitis seemed to fit into the conventional conception, with average success with radical surgical therapy. Four consecutive patients given such treatment in 1932 recovered and made the current ideas on pathology and management seem satisfactory.
GALLOWAY TC. INFECTIONS WITH ANAEROBIC STREPTOCOCCI: WITH SPECIAL REFERENCE TO CRANIAL OSTEOMYELITIS. Arch Otolaryngol. 1942;36(4):514–525. doi:10.1001/archotol.1942.03760040068007
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