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Infection of the middle ear is usually benign but occasionally may lead to considerable involvement of the temporal bone or may extend to the brain, the brain coverings or the blood vessels.
Since the advent of chemotherapy there has been controversy concerning the treatment of otitis media and early mastoiditis. Before whole-heartedly subscribing to any new form of treatment for a disease, one should know the mortality, the morbidity and the average expectancy of the previous forms of treatment. Acute suppurative and nonsuppurative forms of otitis media usually subside in a few days or a few weeks. Which are the cases in which the disease will subside spontaneously with ordinary simple remedies and expectant treatment? Which are the cases in which the patient must be treated with the more heroic and more dangerous methods of surgery or chemotherapy? It is not my intention to detract from the known advantage that
CIRILLO AA. MASKING OF THE PATHOLOGIC STATUS IN OTITIS MEDIA BY CHEMOTHERAPY. Arch Otolaryngol. 1942;36(4):541–547. doi:10.1001/archotol.1942.03760040095009
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