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In a detailed monograph, Moreira surveys the problem of ozena in Brazil.[ill] Over a period of twenty years the incidence was 3.8 per cent of all patients treated for rhinologic conditions. The disease was encountered more frequently in females than in males, and its occurrence favored the second decade of life.
Heredity acted as a factor merely in transmitting certain predispositions to ozena, but not in transmitting the disease itself. Climatic influences seemed to play a role in its incidence, the disease being encountered more frequently in the mountainous regions, and rarely in the maritime areas. It occurred in all social classes, and contagion was not a factor.
The author elaborates on the various etiologic factors, such as thyroid, ovarian and orchitic dysfunctions. Toxic neuritis and metabolic disturbances are also discussed.
The symptomatology and diagnosis—on the basis of clinical, roentgenologic and laboratory data—are described, and, lastly, therapeusis, both medical and
Ozena (Rinite atrópica fétida). Arch Otolaryngol. 1943;37(2):301. doi:10.1001/archotol.1943.00670030310012
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