Skeletal deformities about the head are frequently the first manifestation of generalized osseous disease; hence the otolaryngologist is often called on to diagnose these syndromes.
In 1891 von Recklinghausen1 described in detail the condition which bears his name. He believed the disease resembled that described by Engel2 in 1864 and Langendorff3 in 1877. In 1884 Davies-Colley4 described a typical case of osteitis fibrosa cystica. Erdheim5 was the first to suggest the relationship of the parathyroid glands to this condition. He believed, however, that the changes in the parathyroid were secondary and that changes in the bone were primary. Mandl6 in 1925 transplanted parathyroid tissue into the abdominal wall of a man who had this disease, hoping to prove Erdheim's theory. Nothing resulted from this procedure, but an exploratory operation on the neck revealed a parathyroid tumor, proving the causation of this disease.
Though this condition has been considered comparatively rare,
FOX N, TAGLIA V. OSTEITIS FIBROSA CYSTICA: DIFFERENTIAL DIAGNOSIS: WITH NOTE ON REPAIR OF A MAXILLARY LESION BY CARTILAGINOUS ISOGRAFT. Arch Otolaryngol. 1943;37(3):377–390. doi:10.1001/archotol.1943.00670030387004
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